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• However, a comparison of cardiovascular events shows a greater risk with rofecoxib compared to naproxen (table 7).
• , rofecoxib, valdecoxib, diclofenac, and ibuprofen).
• Naproxen is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function.
• Therefore, your representztion that naproxen prolongs bleeding time and inhibits platelets identicallyto aspirin is misleading, and minimizes the potential seriousness of this finding.